Alzheimer's disease needs to be diagnosed through brain scans or cerebrospinal fluid testing, which is invasive and expensive. A recent study conducted by the Salglenska Institute at the University of Gothenburg in Sweden, published in the journal Nature Medicine, suggests that dry blood samples collected from fingertips can be used to detect key indicators of Alzheimer's disease. The research team has tested a new method for detecting Alzheimer's disease. This method only requires collecting a few drops of fingertip blood and drying them on a card. The team applied this method to 337 participants to detect proteins and other changes in the brain associated with Alzheimer's disease. The experiment found that the level of p-tau217 in fingertip blood samples is highly consistent with standard blood test results, and can identify cerebrospinal fluid changes related to Alzheimer's disease with 86% accuracy. The other two biomarkers GFAP and NfL were also successfully detected, which is highly consistent with traditional testing methods, and participants can sample on their own without relying on guidance from researchers. The team reminds that this method has not yet reached the clinical application stage and needs further improvement. This simple technology is expected to drive large-scale research and remote detection, and can be applied to populations with Down syndrome (who face a higher risk of Alzheimer's disease) and other groups with insufficient medical resources. (New Society)