According to the latest issue of the Journal of Bone and Joint Research, a research team from Osaka City University in Japan is attempting to use a minimally invasive method to repair spinal fractures. They found that stem cells from adipose tissue can repair fractures similar to those commonly seen in osteoporosis patients. This method is simple and effective, and even complex fractures can accelerate healing, potentially extending the healthy lifespan of patients. At present, this method has only been tested on mice. The research team selected mice with osteoporotic spinal compression fractures in the experiment, extracted stem cells from adipose tissue, induced them to form three-dimensional spheroids, and combined them with bone regeneration material tricalcium phosphate for use. The experimental results showed that the treated mouse spine recovered healthier and stronger, and the activity of genes responsible for bone generation and regeneration was significantly increased. Researchers believe that this indicates that the method not only repairs fractures, but also stimulates natural healing mechanisms in the body. The research team stated that this demonstrates the potential of bone differentiated spheroids prepared using adipose derived stem cells in the treatment of spinal fractures. Due to the fact that stem cells are derived from fat, they have a low burden on the body and high safety, making them particularly suitable for elderly patients. These stem cell collection processes are simple and do not cause excessive physical burden even for the elderly, making them a mild bone disease treatment option. (New Society)