Strengthen original innovation and key core technology research and development. ——Taken from the 15th Five Year Plan, it is suggested that the human brain is a mysterious universe. In this "small world" weighing about 1.4 kilograms, there are 86 billion neurons that control human emotions, language, and movement. It is a "biological computer" that is more precise than any supercomputer. How to link the brain with external devices to help humans achieve their dream of "doing whatever they want and getting what they want"? Brain computer interface is a cutting-edge technology for human-computer interaction and human-machine mixing. When the brain is active, neurons discharge to form brainwaves, and brain computer interfaces directly read brain intentions by recognizing brainwave features, achieving interaction between humans, machines, or external environments. The development of science and technology is not explosive, but requires gradual and long-term efforts. For many years, the neural engineering team at Tianjin University has focused on tackling non-invasive brain computer interfaces. In 2014, the team developed a "miracle worker" robot that controlled the robotic arm through EEG signals, allowing disabled people to regain their grip ability; In 2016, the team's in orbit brain computer interaction system entered space, achieving a breakthrough in human-machine collaboration in extreme environments. Behind these achievements, the team members have been continuously tackling neural signal decoding, algorithm modeling, and hardware integration for over 10 years. During the 14th Five Year Plan period, we turned our attention to the field of brain diseases and achieved real-time "observation" of the brain through brain computer interface technology, integrating "diagnosis monitoring treatment prediction". The development of "Shengong Shenguang" non-invasive intracranial pressure allows doctors to measure the size of intracranial pressure without craniotomy, make timely diagnosis, and greatly reduce the risk of intracranial infection; The "Divine Craftsmanship - Divine Pole" technology uses cerebrospinal fluid circulation dynamics and non-invasive brain computer interface technology to shorten the diagnosis time of hydrocephalus from traditional days to 30 minutes, and greatly reduce patients' medical expenses; The concept of 'divine work - divine heart' can achieve objective diagnosis of mental illnesses such as depression; The "Divine Engineer - Divine Ear" provides closed-loop precise tuning for the implantation of artificial cochlear implants; Shengong Shendiao "uses non-invasive regulation technology to regulate and treat brain diseases, bringing new hope to patients with Alzheimer's disease and emotional disorders; The "Divine Craftsmanship - Dinghai" allows neurological intensive care doctors to develop personalized diagnosis and treatment plans for each neurological disease patient more objectively and accurately, reducing postoperative complications. 2025 is of great significance for the development of brain computer interface technology in China. In April, the first comprehensive clinical trial ward for brain computer interface in China was established in Tianjin; In August, the world's first multi center clinical trial of neurocritical brain computer interface was launched, marking the first breakthrough of brain computer interface technology in the traditional application scope of motor and cognitive function repair, and entering the new field of neurocritical illness. Health is a major concern for every ordinary person, and it is our duty to safeguard their health. Looking forward to the 15th Five Year Plan, the team will focus on brain computer interface technology, carry out systematic research and development from underlying chips and electrodes, core algorithms, to system integration and platform construction, strengthen the cultivation of high-level interdisciplinary talents, and add luster to the construction of a healthy China. The author is the Deputy Director of the School of Medicine and Dean of the School of Pharmacy at Tianjin University. Further reading on how brain computer interface technology can treat a wide range of neurological related diseases, causing a heavy burden on individuals, families, and society. However, the presence of the skull makes the brain the most difficult organ to monitor, and the blood-brain barrier makes traditional brain disease treatment drugs face challenges such as difficult delivery, poor targeting, and strong toxic side effects. Overall, humans still know very little about the pathogenesis of brain diseases, and diagnostic and treatment methods are also very limited. The emergence of brain computer interface technology has provided new ways and means for analyzing and treating brain diseases. On the one hand, brain computer interface technology can enable the nervous system to "speak" and achieve "mind reading" and precise diagnosis of the brain through high-precision decoding of neural signals. For example, brain computer interfaces can accurately capture and decode the patient's motion intention signals of "wanting to lift their hand" or "wanting to grip", and then drive robotic arms, exoskeleton gloves, or computer cursor to achieve "mind control", complete basic actions such as drinking water and eating, and also convert thoughts into text or voice output, allowing patients to regain communication ability. On the other hand, brain computer interface technology can also break through the limitations of the blood-brain barrier and treat brain diseases through physical regulation technology. Currently, many drugs are unable to effectively treat diseases due to their difficulty in penetrating the brain barrier, while brain computer interface technology can achieve precise diagnosis of neural activity, and then work synergistically with drugs through regulatory means. This integrated closed-loop treatment model of "diagnosis regulation" will greatly improve the accuracy and effectiveness of brain disease treatment. (New Society)