The ocean, as the largest natural carbon pool on Earth, absorbs over a quarter of the anthropogenic carbon dioxide emissions each year, effectively mitigating global warming. However, the ocean acidification caused by the continuous absorption of carbon dioxide by seawater poses a serious threat to the ecological balance of the ocean. How to convert this portion of carbon that has entered the ocean into resources that can be utilized by humans and slow down seawater acidification is a common challenge in promoting the development of the "blue economy" and achieving the "dual carbon" goals. The National Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, and the Gao Xiang team of the Institute of Synthetic Biology, together with the Xia Chuan team of the University of Electronic Science and Technology of China, first proposed and verified an "artificial ocean carbon cycle system" based on the coupling strategy of "electrocatalysis+biocatalysis". This system can capture carbon dioxide from natural seawater and convert it into an intermediate that can be directly used for biomanufacturing, and further upgraded into various high-value chemicals and materials. This study takes biodegradable plastic monomers as a demonstration case, which is expected to provide a biomanufacturing platform for a wider range of products such as fuels, pharmaceuticals, and food ingredients. The relevant results were recently published in the international academic journal Nature Catalysis. The first key link of the research is led by the Xia Chuan team from the University of Electronic Science and Technology of China. They utilized electrocatalytic technology to achieve efficient carbon capture from seawater. Faced with challenges such as electrode passivation and salt deposition, the research team has designed a new type of electrolytic device. The experimental results show that the device can operate continuously and stably in natural seawater for more than 500 hours, with a carbon dioxide capture efficiency of over 70%, and can also produce hydrogen gas synchronously. At the same time, the research team successfully developed a bismuth based catalyst with high activity and high formic acid selectivity, which efficiently converts captured carbon dioxide into formic acid through electrocatalysis and continuously obtains high concentration formic acid solution. The second key link of the research is led by Gao Xiang's team of Shenzhen Advanced Academy of Chinese Academy of Sciences. They use biocatalytic methods to convert formic acid solution into bio chemicals that can replace fossil industrial sources. The research team chose the marine Vibrio parahaemolyticus, which has a very fast growth rate, and through long-term evolution and synthetic biology methods in the laboratory, systematically reconstructed the gene circuit of the bacteria. They successfully transformed it into an "engineering bacterium" that can tolerate high concentrations of formic acid and efficiently grow and metabolize using it as the sole carbon source. This engineering bacterium can accurately convert formic acid into succinic acid, the core monomer for synthesizing biodegradable plastic polybutylene succinate (PBS), and lactic acid, the monomer for biodegradable plastic polylactic acid (PLA). In order to verify the carbon flow and industrial feasibility of the entire system, researchers confirmed through carbon isotope labeling experiments that the carbon atoms in the final generated succinic acid molecules come from the initially captured carbon dioxide. On this basis, they conducted scaled up experiments in 1-liter and 5-liter fermentation tanks, successfully achieving the transition of the study from laboratory shaking bottle level to pilot level. It is worth noting that the production of lactic acid in the experiment also provides new possibilities for expanding the diversity of biodegradable plastics. At present, the research team has further synthesized fully biodegradable PBS and PLA based on synthetic bioplastic monomers, and prepared demonstration straw products, demonstrating the industrialization possibility of converting seawater into green materials. Researchers have pointed out that through modular design and combination optimization of electrocatalysis and metabolic pathways, the platform is expected to expand to a diverse range of products such as organic acids, monomers, surfactants, and nutritional ingredients, serving industrial scenarios such as materials, chemistry, medicine, and food. The project co leader Gao Xiang stated, "We hope to transform the abundant carbon resources of the ocean into green and high-value products, in order to achieve multiple goals of carbon reduction, resource utilization, and industrial upgrading. This research also provides important technological support for China to implement the 'dual carbon' strategy and build a maritime power