At Tianjin Jianjia Rehabilitation Hospital, 67 year old Mr. Zhang sat on a rehabilitation training chair, slowly lifting his left arm and steadily picking up a water cup... This was the first time he had completed this movement since suffering from cerebral infarction and hemiplegia for half a year. Helping him is the first interventional brain computer interface assisted human limb movement function repair experiment in China. The experiment was recently led by Professor Duan Feng's team from Nankai University. Duan Feng introduced that researchers used minimally invasive neck vascular surgery to insert electrode scaffolds with a diameter of only 2 millimeters into the cerebral motor cortex blood vessels, and simultaneously implanted wireless power supply and transmission devices, establishing a "brain machine limb" closed-loop pathway. Within two weeks after surgery, patients can achieve hand grasping and other operations through their thoughts, and the system signal transmission stability rate reaches 99.7%. Compared to traditional invasive brain computer interfaces that require craniotomy and electrode implantation, the invasive approach achieves precise acquisition and efficient transmission of brain signals through vascular pathways, just like laying 'optical fibers' in blood vessels, bypassing direct intervention on brain tissue and improving postoperative recovery efficiency while ensuring signal quality, "said Duan Feng. This interventional approach integrates multiple technologies: using biomimetic spider mesh structure electrodes to adapt to vascular pulsation and maintain signal stability; The self-designed wireless power supply closed-loop control platform can achieve device endurance of more than 5 years and reduce the risk of infection; The matching intelligent adaptive decoding algorithm can adjust the output parameters in real time according to the patient's movement intention, making the operation natural and smooth. In the experiment, the research team also proposed a "central peripheral central" neural reconstruction mode, which promotes synaptic regeneration through synchronous electrical stimulation training and significantly improves the efficiency of motor function recovery. Experimental data shows that the patient's grip strength has recovered to 82% of the healthy side. This technology not only enables brain signals to control the affected limb, but also activates potential neural plasticity. ”Pu Muming, academician of the CAS Member, said. From technical proposal to system verification, Duan Feng led the team through years of accumulation. In 2022, the team completed the sheep brain intervention experiment; Complete non-human primate experiments by 2023; In 2024, the complete extraction of implanted sensors in sheep brain will be achieved, laying a systematic foundation for human clinical trials... Step by step, we have embarked on the innovative path of brain computer interface. In July of this year, the Duan Feng team jointly established the "Interventional Brain Computer Information Technology Research Institute" with the Yangtze River Delta National Technology Innovation Center and Jiangsu Nantong Innovation Zone. The research institute will focus on the development, clinical validation, and achievement transformation of brain computer interface technology, promoting the systematic and platform based development of brain computer interfaces. Scientific research should not stop at the laboratory, but should move towards real-life scenarios and benefit society, "said Duan Feng. At present, the team has initiated multi center clinical trials. Meanwhile, specialized disease clinics have been established in Beijing, Wuhan and other places. (New Society)