General Secretary Xi Jinping pointed out that further strengthening science education and engineering education, enhancing the independent training of top-notch innovative talents, and providing talent support for solving China's key core technology research and development. A world-class university with Chinese characteristics should accurately grasp the overall strategic deployment of building an educational powerhouse, vigorously promote the transformation of the concept, paradigm, and methods of running schools and educating talents. Grasp the overall trend, respond agilely to promote the reform of disciplinary and professional setting mechanisms, and grasp the initiative of talent independent training strategy from the source. One is to organize and promote advanced planning and forward-looking layout. Deeply grasp the supply-demand contradiction between the construction of disciplines and majors in first-class universities and the industrial transformation of national scientific and technological development, deeply grasp the development trend of key common technologies such as artificial intelligence, quantum technology, biotechnology, etc., organize and promote the prediction of major scientific propositions and the condensation of major engineering problems, gather advantageous resources, and proactively layout new tracks and highlands for disciplines in the future. The second is to systematically promote the overall architecture and system layout. Closely focusing on the strategic needs of serving as the "main force of basic research" and the "source of major scientific and technological breakthroughs" for talent cultivation in first-class universities, we adhere to the dual helix drive of "humanities technology", actively layout a first-class discipline system around fields such as engineering technology, natural sciences, life medicine, social sciences, humanities and arts, and lay a solid disciplinary foundation for cultivating talents with "scientific, engineering, and humanistic literacy" in the integration of general and specialized fields, and cultivate the scientific imagination, creativity, and grassroots innovation ability of the future generation. The third is to deeply promote cross empowerment and integrated layout. Profoundly grasp the evolution law of disciplinary organizational form "cross fusion generation re cross", actively grasp the strategic needs of the "big science" era, anchor the underlying logic and key variables of disciplinary cross fusion, boldly innovate mechanisms, expand increments, and build a "traditional cross" disciplinary cycle empowerment ecology. Activate the ability of talent development and reconstruct the system of independent talent cultivation based on people-oriented approach. We must closely adhere to the fundamental task of cultivating morality and talents, grasp the strategic urgent need for first-class talents in the great cause of national rejuvenation, and build an education and teaching system that fully stimulates students' subjective initiative and unique creativity in achieving success. One is that the training mode should be built around the development of students. Breaking the experience preset of the talent cultivation system, comprehensively building a highly personalized talent cultivation system, supporting students to independently determine their growth goals, design growth paths, and customize growth plans based on national needs, technological laws, and their own characteristics, and promoting the release of the creative potential of the future generation. The second is to cultivate a rhythm that is centered around the development of students. Breaking the previous linear model of "theoretical learning first, practical innovation later" in the overall training of the entire academic stage, we will construct a science education integration micro circulation cluster of "learning while creating, creating while learning" based on individual policies, guiding and supporting students to dare to iterate cognition, propose propositions, challenge authority through continuous independent practice, and promoting the extraordinary and accelerated growth of the future generation. The third is to cultivate resources that are "centered around the development of students". Breaking down the original disciplinary boundaries, inter school boundaries, industry academia boundaries, and international boundaries, promoting interdisciplinary, industry education integration, and global integration in a comprehensive and effective manner, building a cross domain talent training resource supply system, and promoting the future generation to achieve great success and excellence. Integrating knowledge with action, exploring the paradigm of cultivating top talents. First class universities should be based on the development process of human civilization, focus on the global trend of higher education development, criticize and absorb beneficial experiences from countries around the world, and boldly propose new paradigms for cultivating top talents in first-class universities. One is to understand the laws of history. Deeply understand the important statement that "world-class universities have grown up in serving the development of their own countries", correctly recognize the historical inevitability and limitations of important milestones in the global higher education concept model, and critically inherit and deduce new higher education concepts in the new historical stage with a grand historical perspective. The second is to grasp the characteristics of the times. Deeply understanding the comprehensive challenges brought by the intelligent revolution, returning to the human centered value origin of education, focusing on enhancing the survival, creativity, and symbiotic power of human civilization, proposing new concepts of higher education, and striving to cultivate a vanguard force led by human intelligence to control artificial intelligence and serve the promotion of high-quality and sustainable development of human society. The third is to comprehensively grasp the historical laws and characteristics of the times, summarize and condense the reform practices of world-class universities with Chinese characteristics, boldly explore new models of higher education and new paradigms for cultivating top talents, and better forge a new path for the independent cultivation of outstanding talents in first-class universities. (New Society)