Reporters learned from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences on February 13 that the Chinese scientific research team found two unipodolide (SL) efflux transport genes from sorghum for the first time. After the two genes were knocked out, the resistance of sorghum to the parasitic plant unipodolide was significantly improved. This discovery provides important theoretical basis and genetic resources for cultivating crop varieties resistant to parasitic plants. It is reported that parasitic plants invade the tissues of host plants through special structures, such as suckers, and extract nutrients from them. Among them, monopod metal parasitic plants mainly parasitize monocotyledonous crops such as sorghum, corn, and millet, causing serious harm to crop growth. Cultivating crop varieties that are resistant to the parasitism of goldenrod is of great significance for ensuring grain yield. The parasitic process of Angelica sinensis is extremely concealed and difficult to control. Angelica sinensis seeds can sleep in soil for more than 20 years. Once they sense the release of Angelica sinensis lactone from the host plant, they will quickly germinate and invade the roots of the host plant, establishing a parasitic relationship Xie Qi, a researcher at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, said. In this study, the research team, based on original gene mining techniques and combined with big data analysis and other technologies, identified for the first time two key genes involved in the efflux transport of monocotyledons in sorghum, named SbSLT1 and SbSLT2. Research has found that knocking out these two genes inhibits the process of sorghum releasing monocotyledonous gold lactone, leading to the inability of monocotyledonous gold to germinate normally, thereby significantly improving sorghum's anti parasitic ability. The field experiment results showed that knocking out the SbSLT1 and SbSLT2 genes in sorghum varieties reduced the parasitism rate of monocotyledonous gold by 67% to 94%, and reduced sorghum yield loss by 49% to 52%. This discovery provides new ideas and tools for breeding crops resistant to monoculture parasitism. Further research shows that this approach also has application prospects in cultivating parasitic resistant plant varieties for crops such as corn Xie Qi said that the team will further verify the role of relevant genes in other important crops and promote the promotion and application of related breeding technologies in the future. This research was jointly completed by researchers from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, China Agricultural University and other institutions, and relevant achievements have been published online in the international academic journal Cell. (New Society)