According to the announcement released by the National Medical Products Administration, starting from May 1, 2025, the registration and filing of cosmetics will fully implement a complete version of the safety assessment system. The industry is undergoing a deep transformation from "heavy marketing" to "strong security", and a transformation is quietly unfolding to solve "beauty risks" through technological upgrades. The new regulations have been implemented in an orderly manner. In the laboratory of Nais Group Co., Ltd., Liu Yingzheng, the director of the Innovation and Development Research Institute, led a team to conduct experiments on a newly developed shampoo product. We are the first enterprise to respond to the new regulations, and under the guidance of relevant departments, we have already made sufficient preparations. Although the labor and time costs have increased compared to the past, it is worth it to make consumers use the product safer and more reassuring, "he pointed to a stack of half finger thick testing documents. The complete version of the security assessment system puts forward new requirements for the use of raw material data, risk assessment methods, etc. Deng Juan, a cosmetic evaluation technician at the Zhejiang Provincial Center for Drug and Cosmetic Evaluation, stated that the complete safety assessment still needs to conduct relevant research on product stability, anti-corrosion system, packaging compatibility, etc., and submit relevant testing or evaluation conclusions in the safety assessment report to ensure product safety from multiple perspectives. According to data provided by the Zhejiang Provincial Medical Products Administration (hereinafter referred to as "Zhejiang Provincial Medical Products Administration"), since the beginning of this year, the proportion of complete safety evaluations in newly registered products has increased from 50.8% in February to 70.91% in March, and then exceeded 90% in April. Before and after the implementation of the new regulations, the filing and declaration of enterprises in the province were orderly. For a certain scale enterprise, the complete version of security evaluation is no longer the first time to eat a "crab", and even for some top enterprises, it can be said to be easy to handle. On July 19, 2024, Oushiman Biotechnology Co., Ltd. completed the first cosmetic registration in Zhejiang Province to undergo a complete safety assessment. Since August 2024, we have gradually adjusted the security information submitted for new product registration to a complete version of security assessment data. At present, the company's new product registration requires the submission of complete safety assessment materials. ”Mao Geping Cosmetics Co., Ltd. has shared the progress of related work with the media. Nais Group Co., Ltd. has also conducted full version safety evaluations since September 2024. As of now, a total of 16 products have completed full version safety evaluations (including 14 cosmetics and 2 toothpaste), with a pass rate of 100%. To facilitate a smooth transition to new regulations, Zhejiang Province has launched a series of "policy toolboxes": to ensure standardization, uniformity, and normalization of policy implementation, the Zhejiang Provincial Drug Administration has led the Shanghai Jiangsu Anhui joint development of the "Guiding Opinions on the Management of Domestic Ordinary Cosmetics Filing Materials in the Yangtze River Delta Region", which outlines 16 aspects and 55 specific requirements, and clarifies the key points for the review of complete safety evaluation filing materials. In response to the characteristics of cosmetics products in the province, we focus on the evaluation difficulties of relevant experiments, explore and study the submission guidelines for complete safety assessment data of series of cosmetics products with the same basic formula, and provide 'acceleration packages' for enterprises, "said Man Qing, head of the Cosmetics Supervision Department of the Zhejiang Provincial Medical Products Administration. In response to the uneven technological capabilities of enterprises, the province has innovatively implemented the "tiered combat method", classifying and highlighting key areas according to the time nodes when enterprises plan to submit complete safety assessment materials. At the same time, a three in one expert service team consisting of "policy interpretation+technical guidance+review and pre-approval" will be established to carry out "one-on-one" on-site assistance in various cities and filing clusters, and solve practical difficulties for enterprises on site. In order to dynamically grasp the effectiveness of work, Zhejiang has established a coordinated promotion mechanism that connects the upper and lower levels and responds in a timely manner. It regularly analyzes the progress of safety assessment work throughout the province, ensuring that safety assessment work resonates with each other and steadily moves forward, effectively promoting the formation of a "strong promotion of local supervision and full sprint of enterprise entities". From the implementation of the "six step method" for safety assessment in the early stage of the system, to the focus on building a four-dimensional system of "high-level promotion, comprehensive tackling, on-site assistance, and dynamic supervision" in the later stage, this is the continuous exploration of Zhejiang's adherence to the "reform rice" and innovative supervision work guided by "intelligence". In 2024, the operating revenue, total profit, and export value of the cosmetics manufacturing industry in the province increased by 10.7%, 21.6%, and 11.7% year-on-year, respectively. The export value accounted for 26% of the national total, ranking first in the country. Looking to the future, the new regulations bring opportunities. For enterprises, the complete version of safety evaluation is not only a "big test" for self reform, but also an "opportunity" for a new flight. Instead of watching from afar, it is better to take the initiative and embrace the opportunities brought by the new regulations. Switching from a simplified version of security assessment to a full version of security assessment, the industry believes that building enterprise security assessment capabilities should focus on the long-term future. May 1st is a new starting point, and the level of enterprise safety assessment capabilities needs to be continuously improved. An industry insider suggested that industry associations establish safety assessment resource sharing platforms (such as toxicology databases) to better promote industry development. When it comes to how future cosmetics safety assessment management can better meet the needs of the market and consumers, the relevant person in charge of the Zhejiang Provincial Medical Products Administration stated that cosmetics companies need to continuously improve their own safety assessment system, enhance their safety assessment capabilities, strengthen product pre market safety assessments, implement the main responsibility for product lifecycle management, and improve the level of cosmetics safety protection. Strengthening the infrastructure related to safety assessment requires strengthening the discipline construction of cosmetics safety assessment and the training of professional talent teams. Encourage universities to set up courses related to cosmetics safety assessment and improve the professional talent training system. The complete version of security assessment is not only a regulatory requirement, but also a catalyst for industry upgrading. It lays a solid foundation for the high-quality development of the cosmetics industry by enhancing safety, promoting technological innovation, and strengthening international competitiveness. ”Zhang Yan, the president of the Zhejiang Health Products and Cosmetics Industry Association, stated that the complete evaluation requires higher data requirements, which forces companies to enhance their research and development capabilities. For example, the release of technical guidelines such as physical and chemical stability testing and anti-corrosion challenge testing has standardized the testing process of enterprises and promoted their adoption of more scientific methods. Only with increased R&D investment by enterprises can truly good products stand out. (New Society)